{"id":3704,"date":"2023-11-13T15:01:02","date_gmt":"2023-11-13T14:01:02","guid":{"rendered":"https:\/\/www.uni.lu\/research-en\/blog\/research-areas\/alzheimers-disease\/"},"modified":"2026-05-08T16:12:02","modified_gmt":"2026-05-08T14:12:02","slug":"alzheimers-disease","status":"publish","type":"research-areas","link":"https:\/\/www.uni.lu\/research-en\/research-areas\/alzheimers-disease\/","title":{"rendered":"Alzheimer&#8217;s disease"},"content":{"rendered":"<div class=\"section py-0 static\"><div class=\"section py-0 section wp-block-unilux-blocks-navigation-and-hero py-0\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper container xl:max-w-screen-xl\"><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"9b00a516-e6a0-4b82-bf9a-1a1dcead229d\">\n    <nav\n        id=\"secondary-navigation\"\n        role=\"navigation\"\n        aria-label=\"Secondary menu\"\n        class=\"secondary-nav\"\n    >\n        <button\n            class=\"secondary-nav__button btn btn-solid--primary w-full\"\n            aria-expanded=\"false\"\n            aria-controls=\"secondary-navigation__list\"\n            title=\"The selected page is Overview\"\n            type=\"button\"\n        >\n            <span class=\"btn__name mr-auto\">Overview<\/span>\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n                <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\" \/>\n            <\/svg>\n        <\/button>\n\n        <ul id=\"secondary-navigation__list\" class=\"secondary-nav__list\">\n            <li class=\"secondary-nav__item\">\n    <a\n        href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/alzheimers-disease\/\"\n        target=\"\"\n        rel=\"noreferrer noopener\"\n        class=\"secondary-nav__link isactived\"\n        aria-current=\"page\"    >\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Overview<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a\n        href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/alzheimers-disease\/alzheimers-disease-research\/\"\n        target=\"\"\n        rel=\"noreferrer noopener\"\n        class=\"secondary-nav__link \"\n            >\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Research<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<\/div>\n\n<div class=\"wp-block-unilux-blocks-wrapper max-w-screen-3xl mx-auto section py-0\">\n<section class=\"section no-padding-y wp-block-unilux-blocks-hero\">\n    <div class=\"hero hero--2 hero--overlay-top \">\n        \n<header class=\"wp-block-unilux-blocks-wrapper hero__header\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\"><\/span>\n\n\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"not-to-be-forgotten\"\n    >\nNot to be forgotten<\/h1>\n<\/div>\n<\/header>\n<figure class=\"wp-block-dev4-reusable-blocks-image hero__visual object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6-300x173.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6-1024x589.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6-768x442.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6-1536x884.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2023\/11\/Research_Area_generickfcDq6.jpg 2000w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: cover; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 16\/9; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure>\n<div class=\"wp-block-unilux-blocks-wrapper hero__body\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<p class=\"wp-block-unilux-blocks-plain-text\">Through interdisciplinary research, we aim to unravel the mechanisms of Alzheimer\u2019s disease and translate discoveries into prevention strategies and future therapies.<\/p>\n\n\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list\">\n\n<\/ul>\n<\/div>\n<\/div>\n    <\/div>\n<\/section><\/div>\n<\/div>\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about-alzheimers-disease-research\"\n    >\nAbout Alzheimer&#8217;s disease research<\/h2>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>Dementia has been identified by the World Health Organisation as a major health issue. With an expected increase from currently 55 million cases to about 150 million in 2050, dementia will significantly affect healthcare systems worldwide. Approximately two-thirds of all dementia patients are suffering from Alzheimer\u2019s disease, a neurodegenerative disorder that leads to memory dysfunction, behavioural disturbances, and loss of all higher cognitive functions. To date, the biological mechanisms responsible for this disease remain unclear and neither preventive nor disease-modifying therapies exist.<\/p>\n\n\n\n<p>With age being considered the most important risk factor, this number will increase in the next decades due to the increasing life expectancy. Patients exhibit severe memory impairments, cognitive decline, and neuropsychiatric symptoms. While the clinical symptoms are rather well defined, the molecular mechanisms underlying brain dysfunction in Alzheimer\u2019s are still poorly characterized and there is currently no cure, though first treatments are becoming available that influence the course of disease. At the 8xav福利导航 of Luxembourg, we study the underlying mechanisms of neurodegenerative diseases to ultimately develop new ways of treatment.<\/p>\n\n\n\n<p>We also oversee the national Programme for Dementia Prevention (pdp) funded by the Health Ministry. People suspected of MCI and presenting elevated risk factors can be referred by their physician to pdp to receive tailored measures such as dietary suggestions, sports classes, and memory training. It aims to delay dementia onset in people with mild cognitive impairment (MCI) by establishing a personalized risk profile through memory tests and lifestyle questionnaires and then addressing those risk factors. <br><\/p>\n<\/div>\n\n\n\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"latest-news-on-alzheimers-disease\"\n    >\nLatest news on Alzheimer&#8217;s disease<\/h2>\n\n\n\n<ul class=\"wp-block-unilux-blocks-news-card-group flex flex-wrap -mx-16\"><li class=\" w-full px-16 sm:w-1\/2  wp-block-unilux-blocks-news-card\">\n    <div class=\"ulux-card card-news bg-theme\">\n        <div class=\"ulux-card__container\">\n            <div class=\"ulux-card__visual\">\n                <img decoding=\"async\" class=\"w-full\" src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-300x200.jpg\" srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-768x512.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-300x200.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-1024x683.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-1536x1024.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/03\/18122246\/ADPD_2026_awards_HD-7-2048x1365.jpg 2048w\" sizes=\"(max-width: 768px) 100vw, 768px\" alt=\"\" \/>\n            <\/div>\n\n            <div class=\"ulux-card__body\">\n                <h3 class=\"ulux-card__title break-words\">Prof. Heneka receives the European Grand Prize 2026 for Alzheimer research<\/h3>\n                <div class=\"ulux-card__category break-words\">Awards &amp; Rankings, Research<\/div>\n                <time class=\"ulux-card__date break-words\"\n                        datetime=\"2026-03-26\">26 March 2026<\/time>\n                <div class=\"ulux-card__topic break-words\">Life Sciences &amp; Medicine<\/div>\n                <a class=\"ulux-card__link link-text link-absolute\"\n                    href=\"https:\/\/www.uni.lu\/lcsb-en\/news\/prof-heneka-receives-european-grand-prize-for-research-2026\/\"\n                    target=\"\">\n                    <span class=\"link-text__name\">Learn more<\/span>\n                    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right icon--2xs\"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>                <\/a>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/li>\n\n\n<li class=\" w-full px-16 sm:w-1\/2  wp-block-unilux-blocks-news-card\">\n    <div class=\"ulux-card card-news bg-theme\">\n        <div class=\"ulux-card__container\">\n            <div class=\"ulux-card__visual\">\n                <img decoding=\"async\" class=\"w-full\" src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease-300x225.jpg\" srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease-768x576.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease-300x225.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease-1024x768.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease-1536x1152.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Sex-specific-molecular-changes-in-Alzheimers-Disease.jpg 2000w\" sizes=\"(max-width: 768px) 100vw, 768px\" alt=\"\" \/>\n            <\/div>\n\n            <div class=\"ulux-card__body\">\n                <h3 class=\"ulux-card__title break-words\">Unveiling molecular changes in Alzheimer\u2019s disease that differ between men and women<\/h3>\n                <div class=\"ulux-card__category break-words\">Research<\/div>\n                <time class=\"ulux-card__date break-words\"\n                        datetime=\"2025-01-28\">28 January 2025<\/time>\n                <div class=\"ulux-card__topic break-words\">Life Sciences &amp; Medicine<\/div>\n                <a class=\"ulux-card__link link-text link-absolute\"\n                    href=\"https:\/\/www.uni.lu\/lcsb-en\/news\/molecular-changes-alzheimers\/\"\n                    target=\"\">\n                    <span class=\"link-text__name\">Learn more<\/span>\n                    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right icon--2xs\"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>                <\/a>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"related-research-areas\"\n    >\nRelated research areas<\/h3>\n\n\n\n<ul class=\"wp-block-unilux-blocks-quick-link-highlight quick-link-list\">\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/bioinformatics\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Bioinformatics                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/environment-and-diseases\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Environment &amp; Diseases                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/immune-cells-inflammatory-diseases\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Immunology and Inflammatory Diseases                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/microbiome\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Microbiome                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/parkinsons-disease\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Parkinson&#8217;s Disease                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-highlight-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-areas\/rare-diseases\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__body\">\n                    <span class=\"quick-link__number\">\n                        Rare Diseases                    <\/span>\n                    <span class=\"quick-link__title\">\n                                            <\/span>\n                    <span class=\"quick-link__action\">\n                                            <\/span>\n                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n<section class=\"section section wp-block-unilux-blocks-quick-link-discover-section\">\n    <div class=\"container xl:max-w-screen-xl\">\n        \n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"discover-more\"\n    >\nDiscover more<\/h2>\n\n<ul class=\"wp-block-unilux-blocks-quick-link-discover quick-link-list\">\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/en\/about\/profile\/mission-strategy-values\/#strategic-development-areas\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    Key areas                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/en\/about\/organisation\/faculties-departments\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    Faculties                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/en\/about\/organisation\/centres\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    Interdisciplinary centres                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n<\/ul>\n    <\/div>\n<\/section><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":3719,"parent":0,"menu_order":0,"template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"Alzheimer's disease","uluxPrePostTitle":"Research Area","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"field-of-interest":[44,47,50,53,56],"organisation":[238,236,250,251,254],"authorship":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alzheimer&#039;s disease - Research area I 8xav福利导航 of Luxembourg<\/title>\n<meta name=\"description\" content=\"Navigation Menu Dementia has been identified by the World Health Organisation as a major health issue. 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